Gene Combination Identified As Risk Factor In Success Of Dental Implants.  The health of the your surrounding tissue  and gums affects the success of a dental implant. Therefore identifying and reducing the risk factors is a key step in the implant process. Now a combination of genes has been identified as a possible indicator of greater tissue destruction leading to negative outcomes for implants.  A the article in the current issue of the Journal of Oral Implantology, it reports on a study of individuals with the combination of interleukin (IL)-1 allele 2 at IL-1A-889 and IL-1B+3954. These people are “genotype positive” and are susceptible to increased periodontal tissue destruction.